A comparison of laser photocoagulation with trans-scleral cryotherapy in the treatment of threshold retinopathy of prematurity.
نویسندگان
چکیده
OBJECTIVE The goal of this study was to determine whether there was a significant difference between the visual outcomes of eyes with threshold retinopathy of prematurity (ROP) treated with trans-scleral cryotherapy compared to those treated with laser photocoagulation. DESIGN Extended follow-up study of a prospective, randomized clinical trial. PARTICIPANTS Fifty-two patients with bilateral threshold ROP participated. Follow-up data were available for 25 of these patients. INTERVENTION Patients were randomized to receive cryotherapy in one eye and laser photocoagulation in the other eye. MAIN OUTCOME MEASURES The best-corrected visual acuity of each eye was measured. Best-corrected visual acuities of 20/50 or better were classified as "good" clinical outcomes, whereas those 20/60 or worse were considered "poor" outcomes. A secondary outcome of this study was the spherical equivalent (SE) of each eye's most recent refraction. RESULT At an average follow-up point of 5.8 years (range, 4.3-7.6 years), the odds that an eye treated with laser had a good clinical outcome were 6.91 times greater than for eyes treated with cryotherapy (95% confidence interval, 1.70-28.0; n = 21). Additionally, the laser-treated eyes were less myopic with a mean SE of-3.05 diopters compared to a mean SE of -5.08 diopters for the cryotherapy-treated eyes (P = 0.0072, n = 23). CONCLUSION The authors' study suggests that laser photocoagulation for threshold ROP was more likely to result in a good clinical outcome with better final visual acuity and less myopia compared to cryotherapy treatment.
منابع مشابه
Comparison of treatment results for retinopathy of prematurity by diode laser photocoagulation and cryotherapy – four years of observation
Background: The aim of the study was to compare functional and structural outcomes of treatment for retinopathy of prematurity with diode laser photocoagulation and cryotherapy. Materials and methods: We examined 111 children aged 4 years, treated for retinopathy of prematurity by transpupillary diode laser photocoagulation or cryotherapy. Both functional (visual acuity, orthoptic status) and s...
متن کاملCost-effectiveness of treatment for threshold retinopathy of prematurity.
OBJECTIVE Retinopathy of prematurity (ROP) is a leading cause of adverse visual outcomes in premature infants. Both laser photocoagulation and cryotherapy have been demonstrated in clinical trials to be efficacious in reducing the incidence of visual loss occurring secondary to threshold ROP. Visual data recently have become available concerning the long-term clinical efficacy of both treatment...
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In a retrospective study in preterms treated with either cryotherapy (n= 16, 2000-2001) or laser photocoagulation (n= 19, 2002-2005) for threshold retinopathy, a significant decrease in duration of postoperative ventilation, in postoperative administration of analgesics and in time until regain of full enteral feeding was documented in infants who received laser photocoagulation. We therefore c...
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Intraocular pressure variations after diode laser photocoagulation for threshold retinopathy of prematurity.
PURPOSE To investigate the intraocular pressure (IOP) variations occurring after indirect diode laser photocoagulation for threshold retinopathy of prematurity. DESIGN Prospective, nonrandomized, comparative study. PARTICIPANTS A study group-21 consecutive premature babies (42 eyes) undergoing diode laser photocoagulation for retinopathy of prematurity-and control groups-32 premature babies...
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عنوان ژورنال:
- Ophthalmology
دوره 105 9 شماره
صفحات -
تاریخ انتشار 1998